You don't want to miss this! To permanently access this eBook for free, fill out the short form below. From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved ...

RNA purification is the foundation of virtually every downstream molecular biology application — from RT-qPCR and NGS library prep to in vitro transcription (IVT) for mRNA therapeutics. Yet despite ...

A new review synthesizes evidence that gut microbiota composition and metabolites such as short-chain fatty acids modulate ...

The discovery of chemical modifications to overcome mRNA’s instability and immunotoxicity have enabled mRNA therapeutics to evolve dramatically, reaching clinical trials and the forefront of modern ...

On a recent Thursday afternoon, researchers Lanuza Faccioli and Zhiping Hu wheeled an inconspicuous black and white plastic cooler from an operating room at a hospital in downtown Pittsburgh. Inside ...

Cell-to-cell communication is essential throughout all forms and stages of life, and many communication mechanisms are well studied. However, over the past few years, scientists have found increasing ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Messenger RNA copies and carries instructions from the DNA in the cell’s nucleus to where protein is made. More mRNA usually means more protein — unless the mRNA is unstable and breaks down too ...

A retrospective cohort study found that peripheral blood leukocyte PGLYRP1 mRNA measured within two hours of ICU admission ...

Vaccines have been reliably and affordably protecting people from diseases worldwide for centuries. Until the COVID-19 pandemic, however, vaccine development was still a long and idiosyncratic process ...